Excess Weight Gain in Pregnant Women and Prematurity: A Meta-Analysis

Annisa Fitriana Damalita; Yulia Lanti Retno Dewi; Uki Retno Budihastuti

doi:10.26911/thejmch.2022.07.02.05

Authors

Annisa Fitriana Damalita Master's Program in Public Health, Universitas Sebelas Maret
Yulia Lanti Retno Dewi Faculty of Medicine, Universitas Sebelas Maret
Uki Retno Budihastuti Department of Obstetrics and Gynecology, Dr. Moewardi Hospital, Surakarta

DOI:

https://doi.org/10.26911/thejmch.2022.07.02.05

Abstract

Background: Premature birth as a cause of morbidity and mortality in neonates. Excessive weight gain in pregnant women is considered a risk factor for adverse pregnancy outcomes including preterm birth. This study aims to analyze the effect of excess weight gain in pregnant women on premature birth.

Subjects and Method: This research is a systematic review and meta-analysis. Article searches were conducted using electronic databases such as Google Scholar, PubMed, Science Direct and Springerlink. The articles used are articles published from 2011-2021. The keywords to search for articles were: “gestational weight gain” AND “pregnancy” AND (“preterm birth” OR “premature birth”) AND “cohort study” AND “adjusted odds ratio”. The inclusion criteria used were full text articles in English with a cohort study design, multivariate analysis with Adjusted Odds Ratios (aOR), research subjects were pregnant women, intervention was excessive weight gain, comparison was normal weight gain (adequate). , the study outcome was preterm delivery (<37 weeks). The article search results are listed in the PRISMA diagram and analyzed using the Review Manager 5.3 application.

Results: A total of 10 cohort study articles from China, Indonesia, Canada, Korea, Mexico, Puerto Rico, Saudi Arabia, and Taiwan were selected for systematic review and meta-analysis. The results showed that excess weight gain in pregnant women increased the risk of preterm birth and was statistically significant (aOR= 1.23; 95% CI= 1.01 to 1.48; p= 0.030).

Conclusion: Excess weight gain in pregnant women increases the risk of premature birth.

Keywords:

excess weight gain, premature birth, meta-analysis

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